Organophosphate pesticides are neurotoxins. They are commonly used in agriculture areas. The two most commonly used organophosphate insecticides are Chlorpyrifos and Diazinon. Their use in domestic spraying were banned by the EPA, largely because of neurological injury to children. Children in New York displayed autistic spectrum disorders such as ADH and ADHD. The most recent contribution has come from CHAMACOS of California. Seven year olds exposed in utero were tested for neurocognitive deficits. The study concludes: “Prenatal but not postnatal urinary DAP concentrations were associated with poorer intellectual development in 7-year-old children. Maternal urinary DAP concentrations in the present study were higher but nonetheless within the range of levels measured in the general U.S. population..”
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Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children.
Bouchard MF, Chevrier J, Harley KG, Kogut K, Vedar M, Calderon N, Trujillo C, Johnson C, Bradman A, Barr DB, Eskenazi B.
University of California-Berkeley, Center for Environmental Research and Children’s Health, School of Public Health, Berkeley, California 94704, USA.
Organophosphate (OP) pesticides are neurotoxic at high doses. Few studies have examined whether chronic exposure at lower levels could adversely affect children’s cognitive development.
We examined associations between prenatal and postnatal exposure to OP pesticides and cognitive abilities in school-age children.
We conducted a birth cohort study (Center for the Health Assessment of Mothers and Children of Salinas study) among predominantly Latino farmworker families from an agricultural community in California. We assessed exposure to OP pesticides by measuring dialkyl phosphate (DAP) metabolites in urine collected during pregnancy and from children at 6 months and 1, 2, 3.5, and 5 years of age. We administered the Wechsler Intelligence Scale for Children, 4th edition, to 329 children 7 years of age. Analyses were adjusted for maternal education and intelligence, Home Observation for Measurement of the Environment score, and language of cognitive assessment.
Urinary DAP concentrations measured during the first and second half of pregnancy had similar relations to cognitive scores, so we used the average of concentrations measured during pregnancy in further analyses. Averaged maternal DAP concentrations were associated with poorer scores for Working Memory, Processing Speed, Verbal Comprehension, Perceptual Reasoning, and Full-Scale intelligence quotient (IQ). Children in the highest quintile of maternal DAP concentrations had an average deficit of 7.0 IQ points compared with those in the lowest quintile. However, children’s urinary DAP concentrations were not consistently associated with cognitive scores.
Prenatal but not postnatal urinary DAP concentrations were associated with poorer intellectual development in 7-year-old children. Maternal urinary DAP concentrations in the present study were higher but nonetheless within the range of levels measured in the general U.S. population
OTHER REFERENCES ON OPs AND NEUROLOGICAL INJURY TO CHILDREN
The papers listed below are only examples of the multiplicity of published research on this subject
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pesticides are neurotoxins-cause Schizophrenias